(Senior) Scientist - Biophysical Assays

(Senior) Scientist - Biophysical Assays

Selvita

Kraków, Poland

As a member of the assay development team, you’ll play a vital role in the optimization, validation and troubleshooting of biophysical assays to investigate interactions between different classes of proteins and small molecule ligands. You’ll be working in a dynamic, friendly and collaborative environment created by open-minded people, with an everyday opportunity to improve both scientific and organizational skills. The position is app. 70% laboratory work. Join us at Selvita, where these values guide our mission to advance drug discovery to the clinical stage of drug development.

Key responsibilities

  • Conceptual and laboratory work in the area of protein-based assays and biophysics (96w – 1536w plate format);
  • Assay development and supervision/consulting/mentoring of the younger team members in planning and execution of biophysical assays (SPR, MST, ITC, BLI);
  • Introduction of novel and optimization of existing SOPs and protocols to study molecular interactions between proteins and small molecule compounds;
  • Interdisciplinary communication within the company;
  • Literature search and analysis.

Your background

  • Completed university degree (MSc or Ph.D.) in the field of biochemistry, biophysics, biotechnology or related;
  • Minimum 2 years of laboratory experience in drug discovery/biotech/pharma industry;
  • Hands-on experience with SPR, MST, ITC, and BLI as well as FI, LUM, TR-FRET, ALPHA, and FP readout technologies;
  • Experience in fragment-based and ligand-based screening campaigns;
  • Advanced knowledge in the field of binding kinetics and macromolecular interactions;
  • Analytical thinking approach, literature and patent search skills;
  • Ability to work in a team and a very good organization of work;
  • Good spoken and written English.

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