Senior Scientist (Ligand Binding/HAI)

Moderna

Oxford, United Kingdom

Job Description:

The Role:

Joining Moderna offers the unique opportunity to be part of a pioneering team that's revolutionizing medicine through mRNA technology with a diverse pipeline of development programs across various diseases. As an employee, you'll be part of a continually growing organization working alongside exceptional colleagues and strategic partners worldwide, contributing to global health initiatives. Moderna's commitment to advancing the technological frontier of mRNA medicines ensures a challenging and rewarding career experience with the potential to make a significant impact on patients' lives worldwide.

Moderna's strategic partnership with the UK Government is exemplified by our innovative presence at Harwell. Our mission is to establish a leading-edge research, development, and manufacturing facility as part of a long-term commitment to onshore mRNA vaccine production for respiratory diseases. This initiative will create a multitude of highly skilled jobs and foster collaboration with academic and NHS partners across the UK. We're looking for global experts eager to join us in this endeavor, contributing to a future where access to life-saving vaccines is a reality for all.

Moderna is seeking a talented, experienced, and motivated Senior Scientist to join the Immuno-Assays group to serve as a scientific expert and point of contact for the oversight of Immuno-Assay development, qualification/validation to support programs across multiple therapeutic areas. The Senior Scientist will lead a team in the design and execution of immunoassay development, qualification or validation, and the running of clinical samples to return high-quality data for clinical trials conducted by Moderna.

Here's What You’ll Do:

Your key responsibilities will be:

Providing scientific strategies to implement new immune assays (MSD, ligand binding, Multi/single plex assays).
Serving as a lead in the execution of multiple projects requiring immunoassay expertise.
Formulating novel solutions for the design of complex experiments, including ex vivo assays.
Demonstrating technical excellence and advancing high-quality scientific principles in immunoassays.
Conducting ex vivo experimental work for functional profiling of the immune system.
Performing quality review of experimental reports and ensuring staff compliance with safety and regulatory guidelines.

Your responsibilities will also include:

Researching scientific and technical literature to propose and implement innovative solutions applicable to the Laboratory.
Assessing staff strengths and development needs, assigning projects accordingly.
Identifying and resolving quality issues and performing quality review of study reports.
Attending technical conferences and exhibits as required.

The key Moderna Mindsets you’ll need to succeed in the role:

Pursue options in parallel: Your role will require effectively managing multiple tasks and projects concurrently, ensuring the best outcomes through a comprehensive approach.
Dynamic range: Demonstrating the capacity to drive both strategy and execution, adapting swiftly to new data and changing priorities.

Here’s What You’ll Bring to the Table:

Ph.D. (2+ years in immunology or related field) or MSc with more than 4-6 years’ experience in conducting assay validation in clinical Immunology under GLP/GCLP environment.
A background in infections in diseases or oncology and experience with handling laboratory pathogens as containment level 3 is an advantage.
Experience wilt single and multi-plex assays including MSD platform.
Strong level of understanding and expertise in design and executing immune-related studies and assays.
The ability to work in a cross-functional work environment is critical; strong leadership skills and independence skills are expected.
Excellent written, presentation and interpersonal communication skills; ability to influence and collaborate in a team environment and with external stakeholders.
Candidate will be curious in exploring new technology, bold in proposing creative experimental designs and ideas. Will work collaboratively with multifunctional teams and will be relentless in pursuing successful outcomes.
Possess strong computational skills, preferably experienced with Word, Excel, Power Point, GraphPad Prism.
Knowledge of system software for data analysis and statistical analysis.
Experience of working in a regulated environment GLP, GCP, ISO standards is preferred.

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