Ablynx is seeking a (Senior) Research Associate to strengthen the dynamic Bioanalysis and Immunogenicity team. The focus of this department is the development of bioanalytical methods to be used for determination of compound levels and immune responses in biologic samples from pre-clinical and clinical studies. The main responsibilities for this role will be the development, optimisation and validation of pharmacokinetic (PK) and immunogenicity assays (ADA) and their use to analyse samples in (pre)-clinical studies. The successful applicant will be involved in designing, executing and analyzing experiments to evaluate the in vivo behavior of novel drug candidates in a bioanalysis laboratory. Since these methods can be used in support of regulated (GLP/GCP) studies an understanding of GLP principles will be an advantage.
The position requires excellent laboratory skills, critical thinking, and attention to detail at the bench and the desk. The position is primarily a laboratory position. Some documentation help (compiling/review of data tables and reports/instrument maintenance and documentation) will also be required.
You will be involved in the in-depth characterisation of Nanobodies® for various therapeutic applications and your responsibilities will include: