Target Discovery Project Leader

Beatson Institute for Cancer Research

Target Discovery Project Leader

Beatson Institute for Cancer Research

Glasgow, United Kingdom

Salary Range £37,268 - £63,917 depending on experience

The Drug Discovery Unit at the Beatson Institute in Glasgow, is a Cancer Research UK funded group of ex-industry and specialist academic scientists in Biology, Chemistry and Structural Biology. The aim of this unit is to work closely with local cancer experts to maximise the opportunity to develop new and innovative therapies that strike at the core of cancer pathology. Using state of the art screening and structural biology technology, industry standard medicinal chemistry and complex biological modelling systems, the Drug Discovery group at the Beatson is tackling some of the most challenging targets in cancer biology today.

A rare opportunity has arisen to appoint a senior oncology drug discovery biologist to develop and lead a Target Discovery initiative within the group. We are looking for a highly experienced oncology biologist with a track record of identifying and validating novel targets. You will have worked in industry or an equivalent translational drug discovery setting and demonstrated effective leadership within a biology team. If you are an accomplished, enthusiastic scientist and strategic thinker who takes an innovative and proactive approach to research challenges, then we would like to hear from you.

The role will involve networking across multiple research groups, both within the Beatson Institute and the wider UK cancer network in order to understand the research landscape and identify the most promising new drug target opportunities. You will be expected to have a keen interest in drug discovery, and the clinical landscape and future direction of cancer therapeutics. As an oncology biologist, you will have a track record of developing cell biology assays and using molecular biology techniques to explore cancer biology and validate novel drug targets. Ideally, you will also have a clear knowledge of in vivo models of cancer and the molecular techniques required to generate these models.

A demonstrable knowledge of robust experimental design, an ability to pick out the key experimental findings and an innovative and forward thinking approach to experimental challenges are essential for this role.

Skills and Experience:

  • Ph.D. in a relevant biological discipline;
  • Additional experience within the pharmaceutical industry or an equivalent translational drug discovery setting;
  • Demonstrable experience of target identification and target validation, gained in an oncology setting;
  • Experienced in a wide range of mammalian cell culture systems including both 2D and 3D and involving a diverse range of cancer cell types;
  • Experienced in applying molecular biology techniques such as siRNA, shRNA and CRISPR to assess target dependency;
  • Deep understanding of cancer biology, cell pathology and signalling pathways;
  • Excellent communication and leadership skills, including experience of working as part of multidisciplinary team are highly valued.

Applications must be made via our website http://www.beatson.gla.ac.uk/Careers/Drug-Discovery/.

Informal enquiries are welcome and should be addressed to Dr Heather McKinnon; h.mckinnon@beatson.gla.ac.uk (Joint Head Drug Discovery).

Closing date for applications is July 12th, 2019.

Don't forget to mention EuroPharmaJobs when applying.

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© EuroJobsites 2019

EuroJobsites is a UK registered company number: 4694396 VAT number: GB 880 9055 04

Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

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