(Senior) Technician
(Senior) Technician
uniQure
Amsterdam, Netherlands
uniQure is dedicated to bring innovative therapies or unmet medical needs to patients. In doing so each function in uniQure is directly or indirectly responsible for the lives of patients. This responsibility should be part of our day-to-day working life by (i) living up to high quality standards and (ii) by recognizing the sense of urgency in areas of high medical need.
Place in the Organization:
uniQure is dedicated to bringing innovative therapies or unmet medical needs to patients. In doing so each function in uniQure is directly or indirectly responsible for the lives of patients. This responsibility should be part of our day-to-day working lives by (i) living up to high quality standards and (ii) by recognizing the sense of urgency in areas of high medical need.
The New Therapeutics Target Discovery Group has two functions and responsibilities (a) exploring and establishing novel gene therapy technologies (b) development of therapeutics based on the RNAi machinery. Those activities include appropriate proof-of-concept studies as well as the identification of therapeutic target leads.
The group is a major contributor to the quality monitoring of uniQure’s AAV-based products as well as value generator by delivering new technologies and therapeutic targets. Those activities are supporting the whole scope of AAV product development and have to be recognized as the explorative start of a project.
As a senior technician you are involved in practical lab work, data analysis and reporting and support of other lab members. You work according to the specific needs of the Research department and Project Groups.
Key result areas (major duties, accountabilities and responsibilities)
- Executes the experimental work as planned by the Senior Scientist with little supervision;
- The Senior Technician is involved in practical lab work, data collection, analysis, writing and managing documentation for internal purposes (analysis and recording of data and writing reports);
- Explores new technologies that can be applied;
- Recognises day-to-day problems and proposes solutions based on standard and novel procedures;
- Participates in policy and planning initiatives at local project to global company level;
- Educates and supports other lab members, organizes and participates in general lab tasks and activities;
- Communicates the work and results obtained to the Senior Scientist and Director of the R&D Department.
Qualifications & Skills
- BSc or MSc in Life Sciences, Molecular and/or Cell Biology, with a minimum of 5 years of relevant work experience in a comparable position;
- Strong experience in molecular, cellular and biochemical analyses, e.g. cloning, transfection, cell culture, DNA and RNA isolation, PCR, Q-PCR, RT-QPCR, ELISA and western blotting;
- Knowledge on AAV production and purification is a plus;
- Experience to work in a fast changing and demanding environment, willing and able to act pro-actively;
- Hands-on attitude;
- Enthusiastic, able to educate and support other lab members with information and practical work;
- Animal experience (art. 13 or 9 Dutch law on animal experimentation) is a plus;
- Excellent knowledge of the English language (verbal and written).
Core competencies
- Excellent and neat lab working skills;
- Detail oriented/eye for detail;
- Analytical and problem-solving skills;
- Pro-active attitude, adaptive and professional;
- Sound analytical thinking, planning, prioritization, documentation and execution skills;
- Self-organized and able to work in a team;
- Ability to read and keep abreast of technical developments;
- Ability to handle multiple tasks under performance and time-related stress required;
- Ability to train and support other team members;
- Flexible.
